Some topical treatments require you to file down the surface of the nail to help the treatment get through to the nail bed. Avoid using raw garlic as it can cause chemical burns. Nail fungus can cause discoloration, and misshapen your toenails, causing them to thicken and crumble. Baking soda may be suggested by advocates as a remedy, as it can absorb moisture which may cause toenail and nail fungus. Eugenol, which is responsible for most clove's antiseptic qualities and pain-relieving abilities, is also responsible. Nail fungus can be a persistent problem for many people, even after applying topical treatments. They are often effective in treating mild to moderate nail fungus.